Antibody Therapy For Cancer Treatment and Possible Cancer Cure
Our mission is to provide information about antibody research relating for a cancer cure, involving Antibody Therapy Treatment with an antibody, a substance that can directly kill specific tumor cells or stimulate the body immune system to kill specific cancer tumor cells.
- Targeted therapy is a type of treatment that uses drugs or other substances to identify and attack specific cancer cells without harming normal cells. Monoclonal antibodies and tyrosine kinase inhibitors are two types of targeted therapies being studied in the treatment of breast cancer.
Over the years, antibody therapy had been an option for possible cure and treatment of cancer. This method of treatment is a result of the years of dedicated research and understanding of the differences between normal cells and cancer cells. In the present time, cancer treatment primarily focused on rapidly killing cells that are dividing. One characteristic of cancer cells is that it rapidly divides. Moreover, some of the normal cells in the body rapidly divide as well resulting to multiple side effects.
Through antibody therapy, other features of cancer cells are possibly identified. Experts continue to research for the specific differences between the normal cells and the cancer cells. The therapy functions as a killer to attack the cancer cells without getting the normal cells damaged. It also works for fewer side effects in the patient’s body.
Every type of antibody therapy works differently in some cases but all types interfere with the capability of the cancer cells to divide, grow, repair, and communicate with other cancer cells as well. Among the modern types of antibody therapy today uses anti-angiogenesis drugs and monoclonal antibodies. The anti-angiogenesis drugs target the blood vessels supplying the oxygen to the cells. In this process, the cancer cells ultimately get starved.
Some antibody therapies basically focus on the internal function and components of the cancer cells. These therapies use tiny molecules that get into the cancer cells and disrupt its function or cause them to die. Some antibody therapies target the receptors staying outside of the cancer cells. These therapies are also called as monoclonal antibodies.
The monoclonal antibodies are modern types of cancer therapy. The human’s immune system has a component called as antibodies, which are created by the body and act the antigen against germs entering the body. However, monoclonal antibody therapy can only be applied to cancers wherein antigens are already identified.
The anti-angiogenesis therapy for cancer treatment works by stopping the creation of new blood vessels. In normal tissues, new blood vessels are formed during tissue repair and growth such as in a healing wound. New blood vessels are also formed during the development of baby while pregnant. These blood vessels transmit the nutrients and oxygen to the tissues that are essential for survival and growth of the body. Apparently, in cancerous tissue, the tumors require blood vessels in order to spread and grow. In a more complicated process, the endothelial cells divide, develop, and form new blood cells. This process occurs both in cancerous tissue and healthy tissue.
Antibody therapies also protect patients against infections caused by cancer as well as other diseases. These therapies are experiencing huge abandonment in the recent time however plenty of antibody preparations are still being used clinically. Today, the use of antibody therapies to treat infectious diseases is now being facilitated by the fact that such therapies work to provide outright immunity against biological artilleries. These therapies are also facilitated by the relative inefficacy and wide dissemination of microorganisms that are drug-resistant, and the emergence of new microorganisms.
Monoclonal antibody therapy is a cancer treatment that uses antibodies made in the laboratory, from a single type of immune system cell. These antibodies can identify substances on cancer cells or normal substances that may help cancer cells grow. The antibodies attach to the substances and kill the cancer cells, block their growth, or keep them from spreading. Monoclonal antibodies are given by infusion. They may be used alone or to carry drugs, toxins, or radioactive material directly to cancer cells. Monoclonal antibodies may be used in combination with chemotherapy as adjuvant therapy.
Trastuzumab (Herceptin) is a monoclonal antibody that blocks the effects of the growth factor protein HER2, which sends growth signals to breast cancer cells. About one-fourth of patients with breast cancer have tumors that may be treated with trastuzumab combined with chemotherapy.
Tyrosine kinase inhibitors are targeted therapy drugs that block signals needed for tumors to grow. Tyrosine kinase inhibitors may be used in combination with other anticancer drugs as adjuvant therapy.
Complications of Replacement Therapy for Hemophilia
Complications of replacement therapy include:
- Developing antibodies (proteins) that act against the clotting factor
- Developing viral infections from human clotting factors
- Damage to joints, muscles, or other parts of the body resulting from delays in treatment
Antibodies to the clotting factor. Antibodies can destroy the clotting factor before it has a chance to work. This is a very serious problem. It prevents the main treatment for hemophilia (replacement therapy) from working.
Antibodies to clotting factor, also called inhibitors, develop in about 20 percent of people who have severe hemophilia A and 1 percent of people who have hemophilia B.
When antibodies develop, doctors may use larger doses of clotting factor or try different clotting factor sources. Sometimes, the antibodies go away.
Researchers are studying ways to deal with antibodies to clotting factors. They also are studying whether a larger single-dose of clotting factor may be better than repeated, smaller doses for some patients.
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